Drosophila CYP6g1 and its human homolog CYP3A4 confer tolerance to methylmercury during development
نویسندگان
چکیده
منابع مشابه
A homolog of Drosophila Notch expressed during mammalian development.
Drosophila Notch and the related Caenorhabditis elegans proteins lin-12 and glp-1 function as mediators of local cell-cell interactions required for cell-fate decisions during invertebrate development. To investigate the possibility that similar proteins play determinative roles during mammalian development, we isolated cDNA clones encoding rat Notch. The deduced amino acid sequence of this pro...
متن کاملMethylmercury and Human Embryonic Development
Methylmercury (MeHg) is an organic form of mercury that can damage the developing brains of human fetuses. Women who consume methylmercury during pregnancy [2] can bear children who have neurological issues because methylmercury has toxic effects on the nervous system during embryonic development. During the third week of gestation [3], the human nervous system begins to form in the embryo. Dur...
متن کاملMethylmercury and Human Embryonic Development
Methylmercury (MeHg) is an organic form of mercury that can damage the developing brains of human fetuses. Women who consume methylmercury during pregnancy [2] can bear children who have neurological issues because methylmercury has toxic effects on the nervous system during embryonic development. During the third week of gestation [3], the human nervous system begins to form in the embryo. Dur...
متن کاملMethylmercury and Human Embryonic Development
Methylmercury (MeHg) is an organic form of mercury that can damage the developing brains of human fetuses. Women who consume methylmercury during pregnancy [2] can bear children who have neurological issues because methylmercury has toxic effects on the nervous system during embryonic development. During the third week of gestation [3], the human nervous system begins to form in the embryo. Dur...
متن کاملMethylmercury and Human Embryonic Development
Methylmercury (MeHg) is an organic form of mercury that can damage the developing brains of human fetuses. Women who consume methylmercury during pregnancy [2] can bear children who have neurological issues because methylmercury has toxic effects on the nervous system during embryonic development. During the third week of gestation [3], the human nervous system begins to form in the embryo. Dur...
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ژورنال
عنوان ژورنال: Toxicology
سال: 2012
ISSN: 0300-483X
DOI: 10.1016/j.tox.2012.06.001